Calculating your HOMA-IR score is straightforward if you have two specific lab values: your fasting glucose and fasting insulin. While you can always use our HOMA-IR calculator, knowing the formula is useful.

The Formula

The standard formula used globally (when glucose is in mg/dL) is:

HOMA-IR = (Fasting Glucose mg/dL × Fasting Insulin μU/mL) / 405

If your lab reports glucose in mmol/L (standard in the UK, Canada, Australia), the formula changes slightly:

HOMA-IR = (Glucose mmol/L × Insulin μU/mL) / 22.5

Step-by-Step Example

Let's say your lab results are as follows:

  • Fasting Glucose: 95 mg/dL
  • Fasting Insulin: 12 μU/mL

Calculation:

  1. Multiply 95 by 12 = 1140
  2. Divide 1140 by 405 = 2.81

Your HOMA-IR score would be 2.81. According to standard HOMA-IR reference ranges, a score of 2.81 indicates insulin resistance.


Medical disclaimer: This content is for educational purposes only and does not replace individual medical advice.